摘要：We investigated a community-wide outbreak of hepatitis A virus infection in the Shoalhavenregion of the New South Wales south coast. Epidemiological features of the outbreak suggestedthat transmission was predominantly person-to-person. These included: the prolonged courseof the epidemic, the bimodal age-specific attack rate, the lower socioeconomic risk groupsaffected, and the large proportion of cases who reported prior contact with another case.Although widespread use of post-exposure immunoprophylaxis appeared to be effective inpreventing symptomatic infection in individuals, it did not rapidly halt the outbreak. We reviewmethods of mass intervention for community-wide outbreaks of hepatitis A virus infection, anddefine priorities for investigation of future outbreaks
