Welcome to the special issue composed of selected papers from the 2009 IEEE International Conference on Networking, Sensing and Control (ICNSC’09). ICNSC’09 was held at the Okayama University, Japan, March 26-29, 2009. A total of 211 papers were submitted to this conference from different parts of the world. The final program includes 173 papers among which 92 are the contributed papers and 81 are special papers. From this conference, six technical contributions of high quality on intelligent control and system are selected into this special issue. The main contents of the papers are briefly described as follows.