摘要：Recent approval of HPV vaccines and their widespread provision to young women pro-vide an interesting context to gain experience with the application of statistical methods incurrent research. We demonstrate how we have used data extracted from a meta-analysisexamining the efficacy of HPV vaccines in clinical trials with students in applied statis-tics courses at both introductory and intermediate university levels. The data are suitablefor various techniques in categorical data analysis including comparison of proportions,analysis of contingency tables, logistic regression and log-linear models. These data arerelevant to all young people and, because of their health science context, can be used incourses in biostatistics or the health sciences as they allow for further discussion of meta-analyses and randomized controlled trials. We also discuss how we have used these datato promote discussion of statistical issues such as statistical versus practical significance,independence, and a common misconception involving the interpretation of p-values
关键词：Biostatistics; Categorical data analysis; Chi-square test of homogeneity; Ex-periments; HPV; Inference for proportions; Log-linear models; Logistic regression; Meta-analysis; Randomized controlled trials; Relative risk
