摘要:Introduction:Pigweed is a weed which grows in the pastures of Iran. Local people use the plant leaves to cook traditional food. Bermuda grass with its rapid growth and distribution is regarded a real threat to prairies and it can lead to tremors syndrome in cattle and sheep. Burdock which also grows in many parts of Iran is used as a medicinal herb. In this study, the cytotoxicity potential of the three plants was assessed via Artemia Salina test. Methods:Pigweed, Bermuda grass and burdock were collected from Ghaemshahr in the North of Iran. The leaves were dried and the essence of the three plants was extracted. The larvaes were hatched from cysts of Artemia salina at 26.C in filtered seawater. The plant extracts with different concentration (10,100 and 1000ppm) were added to the solution larvaes. Results:The LC50 values (the concentration which needed to die half the larvaes) were measured for pigweed, Bermuda grass and burdock at 1640, 990, and 840 ppm, respectively. Conclusion:The results indicate that compared to the two other species, there is more priority for burdock to be studied in further studies for identification and assessment of toxicity.