期刊名称：Annals of Agricultural and Environmental Medicine
印刷版ISSN：1232-1966
电子版ISSN：1898-2263
出版年度：2009
卷号：16
期号：02
页码：321-324
出版社：Institute of Agricultural Medicine in Lublin
摘要：Coxiella burnetii is an obligate intracellular agent that causes Q fever in hu-mans and animals. The most important reservoirs of C. burnetii in nature are small wild rodents, but infection was also demonstrated in other animals, including ruminants. Sam-ples of blood were obtained from 4 mouflons, 60 fallow deer, 9 Cameroun goats, 8 Car-pathian goats, and 8 Cameroun sheep living in a zoo. Antibodies to phase I and phase II C. burnetii antigens were determined in sera by ELISA. Antibody titres were detected in the range 1:100–1:200. The serum prevalence of phase II and phase I antibodies to C. burnetii antigens was 25% and 0% in mouflons, 70% and 0% in goats, 37.5% and 12.5% in sheep and 28.3% and 5% in fallow deer, resp. Serologic diagnosis of Q fever in animals can be difficult. Some animals may shed C. burnetii and pose a risk for infection prior to the development of antibodies, and some infected animals never seroconvert. The employed ELISA test is a very sensitive assay for C. burnetii, but it is also a labour intensive method and therefore not routinely available
