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  • 标题:Acute respiratory distress syndrome (ARDS) in the course of influenza A/H1N1v infection – genetic aspects
  • 本地全文:下载
  • 作者:Marcin Niemcewicz ; Beata Pająk ; Aleksander Michalski
  • 期刊名称:Annals of Agricultural and Environmental Medicine
  • 印刷版ISSN:1232-1966
  • 电子版ISSN:1898-2263
  • 出版年度:2013
  • 卷号:20
  • 期号:4
  • 页码:711-714
  • 出版社:Institute of Agricultural Medicine in Lublin
  • 摘要:Influenza is a contagious respiratory disease caused by viruses belonging to the family Ortomyxoviridae. Among the influenza viruses type A, B and C, the A type virus shows the most pathogenic potential. Its surface receptor glycoproteins, hemagglutinin (HA) and neuraminidase (NA), are charac terized by high antigenic variation, thus a host organism cannot develop permanent resistance. The case is described of a male patient with severe acute respiratory distress syndrome in the course of influenza A/N1H1v infection, confirmed by virological molecular analysis. During diagnostic procedures based on the MSSCP genotyping it was observed that the WHO recommended RT-PCR kits and/or procedure of sample collec tion from patients for molecular investigation could lead to false positive A/H1N1 pandemic strain detection because of the co-amplification during the RT-PCR fragments of the human genome
  • 关键词:A/H1N1v influenza; complications; respiratory failure; MSSCP genotyping
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