期刊名称:Proceedings of the National Academy of Sciences
印刷版ISSN:0027-8424
电子版ISSN:1091-6490
出版年度:2014
卷号:111
期号:5
页码:1789-1794
DOI:10.1073/pnas.1324168111
语种:English
出版社:The National Academy of Sciences of the United States of America
摘要:DNA polymerase {kappa} (Pol{kappa}) is the only known Y-family DNA polymerase that bypasses the 10S (+)-trans-anti-benzo[a]pyrene diol epoxide (BPDE)-N2-deoxyguanine adducts efficiently and accurately. The unique features of Pol{kappa
关键词:translesion DNA synthesis ; polycyclic aromatic hydrocarbons