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  • 标题:Vitamin D and Cardiovascular Disease
  • 本地全文:下载
  • 作者:Vivian Cristina Garcia ; Lígia Araújo Martini
  • 期刊名称:Nutrients
  • 电子版ISSN:2072-6643
  • 出版年度:2010
  • 卷号:2
  • 期号:4
  • 页码:426-437
  • DOI:10.3390/nu2040426
  • 语种:English
  • 出版社:MDPI Publishing
  • 摘要:Vitamin D insufficiency/deficiency has been observed worldwide at all stages of life. It has been characterized as a public health problem, since low concentrations of this vitamin have been linked to the pathogenesis of several chronic diseases. Several studies have suggested that vitamin D is involved in cardiovascular diseases and have provided evidence that it has a role in reducing cardiovascular disease risk. It may be involved in regulation of gene expression through the presence of vitamin D receptors in various cells, regulation of blood pressure (through renin-angiotensin system), and modulation of cell growth and proliferation including vascular smooth muscle cells and cardiomyocytes. Identifying correct mechanisms and relationships between vitamin D and such diseases could be important in relation to patient care and healthcare policies.
  • 关键词:vitamin D; cardiovascular disease; hypertension
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