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  • 标题:Vitamin A Metabolism and Adipose Tissue Biology
  • 本地全文:下载
  • 作者:Simone K. Frey ; Silke Vogel
  • 期刊名称:Nutrients
  • 电子版ISSN:2072-6643
  • 出版年度:2011
  • 卷号:3
  • 期号:1
  • 页码:27-39
  • DOI:10.3390/nu3010027
  • 语种:English
  • 出版社:MDPI Publishing
  • 摘要:In recent years, the importance of vitamin A in adipose tissue biology, obesity and type II diabetes has become apparent. This review focuses on recent developments within the area of vitamin A and adipose tissue biology. Adipose tissue has an active vitamin A metabolism as it not only stores vitamin A but retinol is also converted to its active metabolite retinoic acid. Several mouse models point to a relationship between vitamin A metabolism and the development of adiposity. Similarly, in vitro studies provide new molecular mechanisms for the function of different forms of vitamin A and retinol- or retinoic acid-binding proteins in adipose tissue.
  • 关键词:retinol; retinoic acid; adipose tissue; cellular retinol-binding protein; beta-carotene; adipogenesis
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