摘要：Enhanced surveillance of invasive meningococcal disease commenced in Queensland in 1999. There were 93 cases,an incidence of 2.8/100,000 population. Most (87%) cases were laboratory confirmed, but 12 per cent were probablecases without laboratory confirmation. The highest age-specific attack rates were in the under 1, 1 to 4 and 15 to 24year age groups. Most of the serologically characterised isolates were group B (70%), followed by group C (24%).There were 12 deaths, resulting in a case fatality rate of 13 per cent. Those who died were more likely to have groupC than group B disease (OR 5.04, CI 1.05-25.14). Only 14 per cent of cases that saw a general practitioner (GP) priorto hospitalisation received parenteral antibiotics, 23 per cent of the 35 cases referred to hospital by a GP receivedpre-hospital parenteral antibiotics and 33 per cent of cases were notified to health authorities within 24 hours ofhospital admission. Thirty per cent were notified two or more days after hospitalisation, delaying the start of publichealth action. Enhanced surveillance has demonstrated a need to promote the use of pre-hospital parenteralantibiotics by GPs and a need to encourage more timely reporting of cases to health authorities
