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  • 标题:Report of the Australian Rotavirus Surveillance Program, 2000/2001
  • 本地全文:下载
  • 作者:Paul Masendycz ; Nada Bogdanovic-Sakran ; Carl Kirkwood
  • 期刊名称:Communicable Diseases Intelligence
  • 印刷版ISSN:1447-4514
  • 电子版ISSN:1445-4866
  • 出版年度:2001
  • 卷号:25
  • 期号:3
  • 页码:143-146
  • 出版社:Government Department of Health and Ageing
  • 摘要:The National Rotavirus Reference Centre together with 15 collaborating laboratories Australia-wide conductedrotavirus surveillance from June 1999. The serotypes of rotaviruses that are responsible for the hospitalisation ofchildren with acute diarrhoea were determined for the period June 2000 to May 2001. We examined 1108 rotavirusspecimens using a combination of monoclonal antibody immunoassay, reverse transcription-PCR, and Northernhybridisation. Serotype G1 strains were the most prevalent overall (49.5%), and found in all centres. Serotype G9rotaviruses, which were first identified in 1997, were second in importance (18.1%). Serotype G2 viruses were next(12.5%), followed by the re-emergence of serotype G4 viruses (9.7%). The findings of this study have implicationsfor vaccine development strategies where protection against serotypes additional to G1-G4 may be required.
  • 关键词:rotavirus; surveillance; serotype; vaccine; gastroenteritis
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