The purpose of this study was to investigate the appropriateness of “English Textbook 2” for Iranian EFL second grade high school students from the teachers’ perspectives. The participants of the study consisted of 25 English teachers (8 females and 17 males) randomly selected from different high schools in Boukan, Iran. The evaluation of the textbook was conducted quantitatively through an adapted checklist developed by Litz (2005). The checklist was a 5-point Likert scale and three criteria including subject and content, activities, and skills out of seven criteria in Litz’s checklist were selected for this study. The results of the study revealed that teachers’ perceptions about these criteria were not favorable in general. The results of this study can be helpful for teachers to use appropriate teaching techniques to compensate for the deficiencies of the textbook and the materials developers and syllabus and curriculum designers in Ministry of Education and other pedagogical experts to revise the current textbook or adopt a new textbook instead.