摘要:Nation-wide surveillance for transmissible spongi-form encephalopathies including Creutzfeldt-Jakob disease (CJD) is undertaken by the Austral-ian National Creutzfeldt-Jakob disease Registry (ANCJDR), based at the University of Melbourne. Surveillance has been undertaken since 1993. During this period the unit has evolved and adapted to changes in surveillance practices and requirements, the emergence of new disease sub-types, improvements in diagnostic capabilities and the overall heightened awareness and understand-ing of CJD and other transmissible spongiform encephalopathies in the health care setting. In 2012, routine surveillance continued. This brief report provides an update on the surveillance data collected by the ANCJDR prospectively from 1993 to December 2012, and retrospectively to 1970. It also highlights the recent release of the revised Australian CJD Infection Control Guidelines.