Background : Rodents are important pests of public health and agricultural importance, capable of transmitting diseases to humans and causing crop damage. The present rodent control strategy depends primarily on synthetic rodenticides, which are highly toxic, affect non-target species, and are expensive. Naturally produced organic pesticides may be more desirable as they are less toxic to non-target animals and are economically sustainable. Objective : The objective of the study is to explore the toxicity and palatability of the bulbs of Drimia altissima against the field rat, Arvicanthis abyssincus with the aim of developing locally based organic rodenticides. Method : This is a laboratory study for evaluating the toxicity of D. altissimia bait against the field rat, Arvicanthis abyssincus. In the study, field rats were randomly assigned to treatment and control groups. The treatment groups received different concentrations of D. altissimia poison bait prepared in the lab. The control groups received the plain bait. Mortality was recorded during the test period.

Results : Of the treatment groups, 80%-100% of the rats receiving the poison bait died, while none of the rats offered a choice between the plain bait and the poisoned bait died. It is estimated that 8% of the powdered bulb would produce 50% mortality. Conclusion : The powdered bulb of D. altissima resulted in rat mortality in the test but not in the control group. The liberation of the toxic substance from the poisoned bait might have been slowed by the presence of the plain bait in the choice test. The result of this study suggests that further work is needed for understanding the toxicological properties of the active agents in the bulb.