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  • 标题:Hematocrit and mean arterial blood pressure in pre- and postmenopause women
  • 本地全文:下载
  • 作者:Beatriz Y Salazar Vázquez ; Miguel A Salazar Vázquez ; Marcos Intaglietta
  • 期刊名称:Vascular Health and Risk Management
  • 印刷版ISSN:1176-6344
  • 电子版ISSN:1178-2048
  • 出版年度:2009
  • 卷号:5
  • 页码:483-488
  • DOI:10.2147/VHRM.S5798
  • 出版社:Dove Medical Press Ltd
  • 摘要:The relationship between mean arterial blood pressure ( MAP ) and hematocrit ( Hct ) was studied in pre- and postmenopause women in the city of Durango, Mexico. Premenopause women show a negative trend between parameters that is not statistically significant. MAP and Hct are directly related in postmenopause women (p < 0.01). It is proposed that that this MAP/Hct relationship is in part due to differences in endothelial function where menopause decreases the capacity of the endothelium to respond to increased blood viscosity and shears stress, leading to the increased production of vasodilator mediators to compensate for changes in blood viscosity due to changes in Hct . Comparison with a large group of postmenopause women in the city of Stockholm showed identical trends.
  • 关键词:menopause; endothelial dysfunction; blood viscosity; blood pressure; hematocrit
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