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  • 标题:Nonobese, exercising children diagnosed with dyslipidemia have normal C-reactive protein
  • 本地全文:下载
  • 作者:Miguel Arturo Salazar Vázquez ; Beatriz Yadira Salazar Vázquez ; M Intaglietta
  • 期刊名称:Vascular Health and Risk Management
  • 印刷版ISSN:1176-6344
  • 电子版ISSN:1178-2048
  • 出版年度:2008
  • 卷号:5
  • 页码:65-72
  • DOI:10.2147/VHRM.S3892
  • 出版社:Dove Medical Press Ltd
  • 摘要:Nonobese children age 10.4 ± 1.1 years diagnosed with dyslipidemia (n = 51) were compared to normal children age 10.8 ± 1.1 years (n = 38). Affected individuals had increased total cholesterol: 223 ± 23 vs 152 ± 17 mg/dl, p < 0.001; and decreased high-density lipoprotein-cholesterol: 41.9 ± 4.1 vs 57.6 ± 5.7 mg/dl, p < 0.001 and triglycerides: 90.8 ± 40.5 vs 65.7 ± 25.0 mg/dl, p < 0.002. Fasting glucose was also significantly elevated (p < 0.02). All other parameters, including blood pressure, were not statistically different between groups. The concentration of C-reactive protein was not statistically different between groups. Analysis of medical records showed that this anomaly may be related to this group (as well as the control group) performing regular, daily exercise. This activity was quantified via a self administered questionnaire, and found to be statistically identical in controls and dyslipidemic individuals. Exercise is associated with the release of antiinflammatory cytokines, therefore our results support the contention that it is a significant factor in promoting health conditions from an early stage in life.
  • 关键词:dyslipidemia; C-reactive protein; children; exercise; inflammation; diabetes; obesity; metabolic syndrome; hispanics
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