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  • 标题:Cardiovascular dysfunction in obesity and new diagnostic imaging techniques: the role of noninvasive image methods
  • 本地全文:下载
  • 作者:José Augusto A Barbosa ; Alexandre B Rodrigues ; Cleonice Carvalho C Mota
  • 期刊名称:Vascular Health and Risk Management
  • 印刷版ISSN:1176-6344
  • 电子版ISSN:1178-2048
  • 出版年度:2011
  • 卷号:7
  • 页码:287-295
  • DOI:10.2147/VHRM.S17801
  • 出版社:Dove Medical Press Ltd
  • 摘要:Obesity is a major public health problem affecting adults and children in both developed and developing countries. This condition often leads to metabolic syndrome, which increases the risk of cardiovascular disease. A large number of studies have been carried out to understand the pathogenesis of cardiovascular dysfunction in obese patients. Endothelial dysfunction plays a key role in the progression of atherosclerosis and the development of coronary artery disease, hypertension and congestive heart failure. Noninvasive methods in the field of cardiovascular imaging, such as measuring intima-media thickness, flow-mediated dilatation, tissue Doppler, and strain, and strain rate, constitute new tools for the early detection of cardiac and vascular dysfunction. These techniques will certainly enable a better evaluation of initial cardiovascular injury and allow the correct, timely management of obese patients. The present review summarizes the main aspects of cardiovascular dysfunction in obesity and discusses the application of recent noninvasive imaging methods for the early detection of cardiovascular alterations.
  • 关键词:cardiovascular risk; endothelium dysfunction; obesity; strain and strain rate; tissue Doppler
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