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  • 标题:The "Pulse Time Index of Norm" highly correlates with the left ventricular mass index in patients with arterial hypertension
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  • 作者:Igor N Posokhov ; Natalya N Kulikova ; Irina V Starchenkova
  • 期刊名称:Vascular Health and Risk Management
  • 印刷版ISSN:1176-6344
  • 电子版ISSN:1178-2048
  • 出版年度:2014
  • 卷号:10
  • 页码:139-144
  • DOI:10.2147/VHRM.S58351
  • 出版社:Dove Medical Press Ltd
  • 摘要:Background: Arterial stiffness, as measured by the pulse wave velocity (PWV), is recommended for routine use in clinical practice as an important parameter for the evaluation of cardiovascular risk.1 New 24-hour monitors (eg, with Vasotens® technology; Petr Telegin Company, Nizhny Novgorod, Russian Federation) provide single PWV measurements as well as several PWV measurements over a period of 24 hours.2 Such 24-hour pulse wave analysis led to the development of the novel Pulse Time Index of Norm (PTIN), which is defined as the percentage of a 24-hour period during which the PWV does not exceed the 10 m/second PWV threshold. The aim of this study is to test the new PTIN for correlation with the left ventricular mass index (LVMI). Methods: Oscillometrically generated waveform files (n=137) used for clinical research studies were reanalyzed using the new 2013 version of the Vasotens technology program, which enables PTIN calculations. Results: A good correlation ( r =−0.72) between the PTIN and the LVMI was shown, which was significantly above the blood pressure load ( r =0.41). Conclusion: The PTIN generated by the Vasotens technology can be recommended as an indicator of end organ damage via hypertension.
  • 关键词:pulse wave velocity; ambulatory; 24-hour; monitoring; PTIN; arterial stiffness; LVMI
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