Teaching courses in a foreign language was formally promoted by Ministry of Education in China in 2001. Guangdong University of Foreign Studies (Guangwai) as a top 3 Chinese foreign language university has taken the lead in teaching business courses in English instruction or bilingual languages. The paper summarizes and analyzes Guangwai’s experiences in implementing this teaching mode, such as the types of courses taught in this mode, the conditions required for teachers, the selection of teaching materials, etc., so as to provide some useful references for the university and other universities.