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  • 标题:POST KALA-AZAR DERMAL LEISHMANIASIS WITH ULCERATION ON FOOT: AN ATYPICAL CASE PRESENTATION SUCCESSFULLY TREATED WITH MILTEFOSINE
  • 本地全文:下载
  • 作者:Vidyanand Rabi Das ; Dharmendra Singh ; Krishna Murti
  • 期刊名称:American Journal of Infectious Diseases
  • 印刷版ISSN:1553-6203
  • 出版年度:2014
  • 卷号:10
  • 期号:2
  • 页码:50-55
  • DOI:10.3844/ajidsp.2014.50.55
  • 语种:English
  • 出版社:Science Publications
  • 摘要:Visceral Leishmaniasis (VL) or Kala-Azar (KA) is highly endemic in the Indian subcontinent particularly in Bihar. Post Kala-azar Dermal Leishmaniasis (PKDL) is a known reservoir for leishmania parasites for transmission of VL. The kala-azar elimination program was launched by the government of three countries of the Indian subcontinent in the year 2005, which aims to eliminate kala-azar by 2015 and PKDL by 2018. PKDL diagnosis and management has not been addressed properly. In this case report we have described a case of PKDL with ulcer and atypical presentation who was subsequently diagnosed by demonstration of Leishmania donovani bodies in the skin snips through microscopy, kinetoplast-DNA nested PCR and clinically. The patient was treated with miltefosine capsules in the dose of 50 mg twice-a-day for twelve-weeks and responded completely. This case report assumes great importance as prompt diagnosis and treatment of PKDL is essential in the kala-azar elimination program.
  • 关键词:PKDL; VL; Miltefosine; Ulcer; Kala-Azar Elimination Program
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