This study empirically investigates the centric view of monetary policy. The study is carried out for Pakistan using annual data covering the period from 2006 to 2012. Fixed effects estimator is applied to investigate the impact of monetary policy measures on banks’ loan supply. We find significant evidence on the existence of the negative relationship between monetary measures and bank loan supply. We also provide empirical evidence that monetary tightening puts more burdens on small banks as compared to large banks. Yet, we observe that during monetary tightening, aggregate lending by all the banks decreases, which consequently decreases the level of investment that affects the growth and output level of the economy. Evidence on monetary transmission is useful for developing the link between the financial and real sector of the economy. This study helps the policy makers to find different channels through which they can increase the effectiveness of monetary policy.