期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：2014
卷号：111
期号：46
页码：16365-16370
DOI：10.1073/pnas.1411086111
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：SignificanceAdipocytes evolve from preadipocyte progenitors by the process of adipogenesis. This process is governed by the adipogenic master regulator peroxisome proliferator-activator receptor gamma (PPAR{gamma}). PPAR{gamma} is also involved in metabolic homeostasis and in pathological states such as obesity and diabetes. Furthermore, a common genetic polymorphism of PPAR{gamma
