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  • 标题:Resuscitation of very preterm infants with 30% vs. 65% oxygen at birth: study protocol for a randomized controlled trial
  • 本地全文:下载
  • 作者:Denise Rook ; Henk Schierbeek ; Anne C van der Eijk
  • 期刊名称:Trials
  • 印刷版ISSN:1745-6215
  • 电子版ISSN:1745-6215
  • 出版年度:2012
  • 卷号:13
  • 期号:1
  • 页码:65
  • DOI:10.1186/1745-6215-13-65
  • 语种:English
  • 出版社:BioMed Central
  • 摘要:Resuscitation at birth with 100% oxygen is known to increase the oxidative burden with concomitant deleterious effects. Although fractions of inspired oxygen (FiO2) 88%, Apgar score at 5 min, cumulative O2 exposure, oxidative stress (as determined by glutathione synthesis and oxidative stress markers), retinopathy of prematurity, brain injury and neurodevelopmental outcome at 2 years of age. This study will provide insight into determining the appropriate initial FiO2 to start resuscitation of very preterm infants. http://www.trialregister.nl , NTR243.
  • 关键词:Preterm infants ; Resuscitation ; Oxygen ; Bronchopulmonary dysplasia ; Oxidative stress ; Glutathione synthesis
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