摘要：Prevalence of diseases, such as cardiovascular disease, obesity, hypertension, diabetes, and even cancer, was affected by dietary factors. Recently there are many comprehensive studies about bioactive peptides formed by food-derived proteins which are the beneficial effects to human health. Those protein particles known as bioactive peptides are released either by digestive enzymes during gastrointestinal transition or by fermentation or ripening during food processing by the way of microorganisms such as starters. Bioactive peptides exhibiting activities such as antimicrobial, antioxidant, antithrombotic, antihypertensive and immunomodulatory affect the major body systems like the cardiovascular, digestive, endocrine, immune and nervous systems. Among different bioactive peptide fractions the ACE inhibitor peptides have a particular importance in western countries in which hypertension prevalence is detected. Nutritional factor has a crucial role in preventing hypertension. Studies have shown that the consumption of foods with antihypertensive peptides decrease the blood pressure, so novel food production having antihypertensive activity is increasingly becoming important. In the industrial applications the way they are added into foods, their corporation organoleptic characteristics, and the stability in storage and food contribution to the processing should be considered. In this article, the milk protein-based of antihypertensive peptides have been investigated in terms of structure, bioavailability and usage possibilities as drug.
