摘要:Resveratrol (3, 5, 4’ trihidroksistilben) is a type of polyphenol which is named as phytoalexin. Polyphenols can be found in skins, seeds and stalks of grapes. Intake of phenolic compounds, especially flavanols through wine consumption is known to have favorable health effects due to their antioxidant properties. Researches show that wine contains resveratrol which is produced under stress conditions as a defense metabolite in grapes. Wine has high amounts of polyphenolic compounds that are known to have protective properties against coronary heart diseases, cancer and inflammation. In-vitro and in-vivo investigations show that red wine has preventive effects on leukemia, skin, lungs and prostate cancers. Recent findings of in-vivo investigations point out that, resveratrol can be an effective agent during the initial, development and progressive phases of cancer. Although there are many researches on determination of resveratrol content of wines in different countries, investigations on this subject are limited in Turkey. In this study, resveratrol contents of wine samples which are produced from grapes grown in different regions of Turkey were determined by High Performance Liquid Chromatography. The results show that resveratrol concentration of the samples changes with according to the type of grapes and the regions they were grown.