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  • 标题:Paraffin poisoning in children: What can we do differently?
  • 本地全文:下载
  • 作者:N Malangu MSc (Pharmacology) ; WJ Du Plooy PhD (Pharmacology) ; GA Ogunbanjo MBBS; MFGP(SA)
  • 期刊名称:South African Family Practice
  • 印刷版ISSN:2078-6190
  • 电子版ISSN:2078-6204
  • 出版年度:2005
  • 卷号:47
  • 期号:2
  • 页码:54-56
  • DOI:10.1080/20786204.2005.10873189
  • 出版社:Taylor and Francis Ltd
  • 摘要:

    Background: The purpose of this study was to describe the occurrence, health cost and management of paraffin poisoning in a rural South African hospital.

    Methods: A retrospective study was undertaken of 145 children admitted with a diagnosis of paraffin poisoning at Philadelphia Hospital, Mpumalanga from January 2000 to June 2001. A pre-tested form was used to collect data from the admission files. Where applicable, the Chi-square test or t-test was used to determine statistical significance.

    Results: Children younger than five years of age were affected significantly more than those older than five years of age (91% vs. 9%, p<0.001), and boys were affected more than girls (58% vs. 42%, p=0.034). The average length of stay and cost of treatment were 2.5±2 days and R617.24 respectively. Prophylactic antibiotics were prescribed in 86% of cases (125/145) and the average number of medications prescribed per child was 3.5±1.8.

    Conclusions: Although no mortality was reported, paraffin poisoning contributed substantially to the morbidity of, health expenditure for and antibiotic overuse in these children. Provision of child-resistant paraffin container caps, retraining of doctors on appropriate antibiotic use and community education are necessary and crucial in reducing the occurrence of paraffin poisoning in children.

  • 关键词:paraffin poisoning ; children ; antibiotic overuse ; South Africa
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