Gloria Anzaldúa’s concept of mestiza consciousness is presented in this article as a form of epistemology that makes non-binary and non-discriminatory reinterpretations of the Western concept of the border possible. Anzaldúa’s rearticulation of the U.S.-Mexican border is contrasted with established U.S. national myths of westward expansion. The writer’s project is further illustrated by a gender- and race-sensitive analysis of the poem “We Call Them Greasers,” carried out from a postcolonial perspective and a feminist position.