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  • 标题:Analysis of Solute Carrier Family 6 Member 4 Gene promoter polymorphism in young Turkish basketball players.
  • 本地全文:下载
  • 作者:Korkut Ulucan ; Sevim Yalcin ; Berkay Akbas
  • 期刊名称:The Journal of Neurobehavioral Sciences
  • 电子版ISSN:2148-4325
  • 出版年度:2014
  • 卷号:1
  • 期号:2
  • 页码:37-40
  • DOI:10.5455/JNBS.1403730925
  • 出版社:International Medical Journal Management and Indexing System
  • 摘要:The serotonin transporter (5-hydroxytryptamine transporter, 5- HTT) gene (SLC6A4) is considered to be one of the most important candidate genes for genetic involvement in psychiatric conditions like anxiety, self- confidence and motivation. In the present study, we aimed to analyze the distribution of SLC6A4 promoter long and short (L and S, respectively) polymorphism in young Turkish basketball players. We enrolled 24 players in the study, 17 were female and 7 were male. 12 %, 35 % and 53 % of the females had SS, LS and LL genotype, respectively; whereas %28,5 of the males had SS and the same percentage of them had LS, and % 43 had LL genotype. When we examine the allelic counts, L allele was recorded as 71% in females and 57% in males; S allele was 29% in females and 43% in males. Our results were in agreement with the previous ones, indicating the presence of L allele in individuals dealing with sport. We suggest that SLC6A4 promoter analysis is important for genetic counseling for the individuals who are prone to be successful in sports.
  • 关键词:Serotonin transporter; sports; genetics; polymorphism
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