期刊名称:Journal of Environmental and Occupational Science
印刷版ISSN:2146-8311
出版年度:2012
卷号:1
期号:3
页码:155-160
DOI:10.5455/jeos.20121209062704
语种:
出版社:International Medical Journal Management and Indexing System
摘要:The influence of volatile organic solvents (nitrocellulose thinner, gasoline and xylene) on the activity quotient and liver biochemical indices of laboratory mice, Mus musculus over a period of 60 days were evaluated. The study entailed the use of a modified nose inhalation exposure method in which the exposure chambers were saturated with the test chemicals for 8 hours daily following which they were transferred to the vapour- free section of the chamber. The estimation of activity quotient by day 60 indicated that mice exposed to xylene were most restless followed by nitrocellulose thinner and gasoline (least restless) with activity quotient values of 0.69, 0.58 and 0.21 respectively. The results of the biochemical indices showed that there was a significant decrease (p