首页    期刊浏览 2024年11月24日 星期日
登录注册

文章基本信息

  • 标题:Antimicrobial drug utilization pattern in neonatal sepsis in a tertiary care hospital
  • 本地全文:下载
  • 作者:Hardik V. Vaniya ; Jitendra M. Agrawal ; Nirav M. Patel
  • 期刊名称:Journal of Clinical & Experimental Research
  • 印刷版ISSN:2320-348X
  • 电子版ISSN:2320-3811
  • 出版年度:2014
  • 卷号:2
  • 期号:2
  • 页码:110-114
  • DOI:10.5455/jcer.201422
  • 语种:
  • 出版社:International Medical Journal Management and Indexing System
  • 摘要:Objective: The objective of this study was to determine antimicrobial drug use in newborns at a tertiary care neonatal intensive care unit, to identify educational/research priorities in neonatal drug therapy. Materials and Methods: This prospective observational study included 713 patients of neonatal sepsis over a period of 18 months. Data like name, age, sex, birth weight, gestational age, antibiotics used were recorded in the previously prepared case record form. Results: Number of patients admitted in early neonatal period was 467(65.5%) and number of patients admitted in late neonatal period was 246(34.5%). The mean age of all patients being admitted in NICU was 6.23 ± 5.86 days. The majority of neonates (92.56%) were prescribed 2 to 5 antibiotics and 29.59% of neonates were prescribed 2 antibiotics. Average number of antibiotics of all patients being admitted was 3.74 ± 1.38. Most frequently used antibiotics in decreasing frequency were: Amikacin (97.19%), ampicillin + sulbactam (60.17%), vancomycin (57.64%), ceftazidime (38.71%), cefotaxime (34.22%), ciprofloxacin (26.23%), piperacillin + tazobactam (19.07%). 73% drugs were given by generic name and 53.33% drugs were prescribed from the essential drug list. Mean length of stay in NICU of all patients being admitted was 7.59 ± 5.66 days. Conclusion: The present study provides valuable insight about the overall pattern of antimicrobial drug use profile in patients of neonatal sepsis of a tertiary care hospital. It is intended to be a step in broader evaluation of safety and efficacy of drug prescription in neonatal sepsis patients.
  • 关键词:Antibiotics; drug utilization; neonate; neonatal sepsis
国家哲学社会科学文献中心版权所有