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  • 标题:Effect of Diazinon on Acetylcholinesterase Activity and Lipid Peroxidation of Poecilia reticulata
  • 本地全文:下载
  • 作者:Archana A. Sharbidre ; Vimal Metkari ; Priyanka Patode
  • 期刊名称:Research Journal of Environmental Toxicology
  • 印刷版ISSN:1819-3420
  • 出版年度:2011
  • 卷号:5
  • 期号:2
  • 页码:152-161
  • DOI:10.3923/rjet.2011.152.161
  • 出版社:Academic Journals Inc., USA
  • 摘要:The present study was undertaken to evaluate the toxicity and effects of a commercial formulation of the organophosphorous insecticide, Diazinon on acetylcholinesterase and lipid peroxidation activity in the freshwater guppy fish Poecilia reticulata . The fish exposed for 96 h to 50, 100 and 150 μg L-1 concentrations of diazinon at 24.0±1.0°C. Some characteristics of this aquarium water were dissolved oxygen , 7.2-7.9 mg L-1 and conductivity, 0.212-0.260 mS. Each exposure involved 3 treatments with 3 replicates and 1 control (without diazinon). In each aquarium (Volume: 5 L) were 10 fishes. Induction of oxidative stress in various tissues was evidence by increased lipid peroxidation levels. Acetylcholinesterase activity responded positively in a concentration dependent pattern, thus, suggesting the use of these two parameters as potential biomarkers of toxicity associated with contaminations exposure in freshwater fishes.
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