期刊名称：Journal of Environmental Science and Technology
印刷版ISSN：1994-7887
电子版ISSN：2077-2181
出版年度：2013
卷号：6
期号：1
页码：57-62
DOI：10.3923/jest.2013.57.62
出版社：Asian Network for Scientific Information
摘要：The current uses of the organophosphorous methyl-parathion (MP) easily allow the pesticide to reach non-target organisms like fish. This substance was previously found as an endocrine disruptor of the Hypothalamus-Pituitary-Interrenal (HPI) axis. Thus, the cortisol response has been investigated in waterborne MP (5.2 mg L-1) exposed adult zebrafish ( Danio rerio ) sampled 96 h after exposure. Stressed fish exposed to MP contaminated water showed lower levels of whole-body cortisol. Data demonstrated that MP produced impairment in the cortisol response to stress in zebrafish. This impairment may reduce the ability of the organism to promote metabolic and ionic adjustments necessary for the stress response. Fish that are incapable of mounting a normal cortisol response are likely to have a reduced ability to respond to the continuous challenges imposed on their homeostatic systems, either by aquaculture practices or by environmental changes.
