Heart transplantation is the last method for the patients who are suffering from heart failure refractory to conventional medical treatment. Traditional contraindications of heart transplantation are irreversible pulmonary arterial hypertension, active infection, irreversible renal, hepatic dysfunction, coexisting neoplasm, psychosocial instability, substance abuse and so on. But these days, traditional contraindications have been changed because increased clinical experience allowed liberalization of patients who were previously considered contraindication. We experienced a case of successful heart transplantation in dilated cardiomyopathy patient with preoperative delirium.