文章基本信息

标题：The effect of carbon dioxide pneumoperitoneum on baroreflex sensitivity
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作者：Chung, Seunghyun ; Cho, Hun ; Kim, Kyoung Ok 等
期刊名称：Korean Journal of Anesthesiology
印刷版ISSN：2005-6419
出版年度：2008
卷号：55
期号：6
页码：662-665
DOI：10.4097/kjae.2008.55.6.662
语种：Korean
出版社：The Korean Society of Anesthesiologists,
摘要：Background
To determine if positive pressure pneumoperitoneum has adverse effects on autonomic nervous system function, we examined baroreflex sensitivity (BRS) during carbon dioxide pneumoperitoneum in patients undergoing laparoscopic surgery.
Methods
Twenty adult patients scheduled for laparoscopic gynecologic surgery were selected for the study. After general anesthesia was induced with sevoflurane, continuous electrocardiography and blood pressure were monitored. Spontaneous BRS was achieved using sequence method immediately before, and 5 minutes after, pneumoperitoneum. Heart rate variability (HRV) was also determined.
Results
After pneumoperitoneum, BRS decreased from 12.9 ± 1.8 ms/mmHg to 8.1 ± 1.1 ms/mmHg (P < 0.05), and the power of the high frequency band decreased from 237.8 ms²/Hz to 49.6 ms²/Hz (P < 0.05).
Conclusions
Compared to recordings obtained before pneumoperitoneum, BRS was decreased during pneumoperitoneum. This may predispose patients undergoing laparoscopic surgery to hemodynamic instability in addition to pneumoperitoneum itself.
关键词：autonomic nervous system; baroreflex sensitivity; carbon dioxide; Laparoscopy; pneumoperitoneum