文章基本信息
- 标题：Optimal sedative dose of propofol to start MRI in children with cerebral palsy
- 本地全文：下载
- 作者：Kim, Eun Jung ; Jo, Youn Yi ; Kil, Hae Keum 等
- 期刊名称：Korean Journal of Anesthesiology
- 印刷版ISSN：2005-6419
- 出版年度：2011
- 卷号：61
- 期号：3
- 页码：216-219
- DOI：10.4097/kjae.2011.61.3.216
- 语种：English
- 出版社：The Korean Society of Anesthesiologists,
- 摘要：Background
This study was designed to determine the optimal sedative dose of propofol to start brain magnetic resonance imaging (MRI) in children with cerebral palsy (CP).
MethodsTwenty children, aged 0.5-5 years, were administered propofol to achieve a University of Michigan Sedation Scale (UMSS) score ≥ 3 in the MRI room. The proper dose of propofol was determined using the up-and-down method.
ResultsThe ED50 and ED95 for successful sedation with a UMSS ≥ 3 were 2.07 mg/kg (95% CI 1.69-2.56) and 2.69 mg/kg (95% CI 2.35-5.59). Respiratory events occurred in 5 patients and were resolved with neck extension, chin lift, or transient respiratory assistance with successful sedation.
ConclusionsLow dose propofol can safely facilitate the initiation of MRI in children with CP.
- 关键词：Cerebral Palsy; MRI; propofol
