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  • 标题:Dilution and slow injection reduces the incidence of rocuronium-induced withdrawal movements in children
  • 本地全文:下载
  • 作者:Shin, Young Hee ; Kim, Chung Su ; Lee, Jong-Hwan
  • 期刊名称:Korean Journal of Anesthesiology
  • 印刷版ISSN:2005-6419
  • 出版年度:2011
  • 卷号:61
  • 期号:6
  • 页码:465-469
  • DOI:10.4097/kjae.2011.61.6.465
  • 语种:English
  • 出版社:The Korean Society of Anesthesiologists,
  • 摘要:Background

    The aim of this study was to evaluate whether slow injection of diluted rocuronium could reduce rocuronium-induced withdrawal movements effectively in children.

    Methods

    After loss of consciousness, rocuronium 0.6 mg/kg was administered into 171 children according to the pre-assigned groups as follows: Group CF, injection of non-diluted rocuronium over 5 seconds; Group CS, injection of non-diluted rocuronium over 1 minute; Group DF, injection of diluted rocuronium (10 times) over 5 seconds; Group DS, injection of diluted rocuronium over 1 minute. An investigator who was blind to the injection techniques recorded patient movements followed by rocuronium injection.

    Results

    The incidence of withdrawal movement in Group CF was highest among the groups (all P < 0.0001). Moreover, withdrawal movement was less frequently observed in Group DS than in Groups CS and DF (P = 0.021 and P = 0.007, respectively).

    Conclusions

    Slow injection of diluted rocuronium reduced the incidence of withdrawal movements in children.

  • 关键词:child; injections; intravenous; Movement; Pain; rocuronium
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