Transurethral resection of the prostate is the gold standard in the operative management of benign prostatic hyperplasia. Bipolar transurethral resection of the prostate using saline solution is a safe technique and reduces the risk of transurethral resection syndrome. This report discusses a rare complication of bipolar transurethral resection of the prostate: the extravasation of 0.9% saline solution into intraperitoneal and retroperitoneal cavities due to bladder perforation, resulting in respiratory difficulties.