To evaluate the prognostic value of multifocal electroretinography (mfERG) after a decrease of retinal thickness in eyes with diabetic macular edema (DME).
MethodsSixty patients (60 eyes) underwent intravitreal injection of triamcinolone acetonide or bevacizumab for diabetic macular edema. Eyes were divided into three groups, according to foveal thickness : Group A (<500 µm, n=20 eyes), Group B (500 µm ≦ <800 µm, n=20 eyes), and Group C (≧800 µm, n=20 eyes). Best-corrected visual acuity (BCVA) and mfERG responses from the most central seven hexagons were analyzed both before and after treatment.
ResultsThe pre-injection P1 amplitudes of mfERG correlated significantly with end-point BCVA in Groups A and B ( p <0.05), but did not correlate with end-point BCVA ( p >0.05) in Group C.
ConclusionsThe level of P1 amplitudes of mfERG may be a useful tool to predict visual outcomes after a decrease of retinal thickness in patients with diabetic macular edema.