文章基本信息
- 标题：The Role of Electroretinography in Assessing the Progression of Diabetic Retinopathy
- 本地全文：下载
- 作者：Park, Su Eun ; Sun, Hae Jung ; Lee, Hyun Joon 等
- 期刊名称：Journal of the Korean Ophthalmological Society
- 印刷版ISSN：0378-6471
- 出版年度：2010
- 卷号：51
- 期号：5
- 页码：693-699
- DOI：10.3341/jkos.2010.51.5.693
- 语种：Korean
- 出版社：The Korean Ophthalmological Society
- 摘要：Purpose
To investigate the clinical significance of electroretinographic (ERG) responses, including the photopic negative response parameter, in assessing the progression of diabetic retinopathy.
MethodsStandard flash ERG was tested on 28 normal controls and 143 patients who were diagnosed with diabetes mellitus. Of those, 97 patients had diabetic retinopathy in different stages. Electroretinography was performed according to the International Society for Clinical Electrophysiology of Vision (ISCEV) standards. Amplitudes and implicit times of ERG responses, including the photopic negative response (PhNR), were compared at different stages of diabetic retinopathy.
ResultsAmplitudes of oscillatory potentials were significantly reduced in mild NPDR. Cone b-wave amplitude, 30-Hz flicker response, and PhNR were significantly reduced in moderate NPDR.
ConclusionsThese results suggest that oscillatory potentials are good indicators of retinal function change in the early stage of diabetic retinopathy, and the appropriate results of the cone b-wave, 30-Hz flicker response and PhNR tests are good indicators of moderate NPDR.
- 关键词：Diabetic retinopathy; Oscillatory potentials; Photopic negative response; Standard electroretinography
