To evaluate the mean macular volume in normal Korean eyes using spectral-domain optical coherence tomography.

The present study consisted of 132 patients (212 eyes) with no ophthalmic evidence of retinopathy and who had a best corrected visual acuity of 1.0 or better. The total macular volume was measured using spectral-domain optical coherence tomography and was analyzed according to age group, sex, degree of refractive error and presence of systemic disease such as diabetes and hypertension.

The mean total macular volume of all subjects was 10.07 ± 0.45 mm³, with means of 10.13 ± 0.40 mm³, 10.05 ± 0.43 mm³ and 9.97 ± 0.58 mm³ measured for the respective A, B, and C age groups. There was a significant difference between male and female patients. In addition, there was a significant difference between diabetic patients in group C and normal subjects. However, there was no significant difference according to degree of refractive error.

The measured value of mean macular volume in normal Korean eyes can be expected to provide a standard value for diagnosing retinal disease and the need for careful follow-up.