To evaluate the repeatability and comparability of anterior chamber depth (ACD) and central corneal thickness (CCT) measurements obtained by Galilei dual Scheimpflug analyzer (Ziemer, Port, Switzerland) and slit-lamp optical coherence tomography (SL-OCT; Heidelberg Engineering, Dossenheim, Germany).

ACD and CCT were measured by Galilei and SL-OCT in 68 eyes of 68 healthy young subjects. Each measurement was performed 3 times by a single examiner, and the repeatability of 3 consecutive measurements was analyzed. ACD and CCT measurements were compared between the 2 devices.

Both Galilei and SL-OCT showed high repeatability (ICCs ≥ 0.994) for ACD and CCT measurements. The mean ACD and CCT measured by Galilei were greater than SL-OCT measurements by 0.11 ± 0.09 mm and 14.01 ± 7.38 µm, respectively. The 95% limit of agreement values for ACD and CCT measurements were 0.36 mm, 27.66 µm, respectively, and were highly correlated (correlation coefficients ≥ 0.89, p < 0.001).

Although the repeatability of each device was high, ACD and CCT obtained by Galilei and SL-OCT were significantly different. These differences should be considered when interpreting ACD and CCT measurements obtained by the 2 devices.