文章基本信息

标题：Two Cases of Topiramate-induced Acute Myopia
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作者：Kim, Seong Wook ; Seo, Seong Gwan ; Her, Jun 等
期刊名称：Journal of the Korean Ophthalmological Society
印刷版ISSN：0378-6471
出版年度：2008
卷号：49
期号：6
页码：1033-1040
DOI：10.3341/jkos.2008.49.6.1033
语种：Korean
出版社：The Korean Ophthalmological Society
摘要：Purpose
We describe 2 cases of bilateral acute myopia associated with topiramate, a drug that has recently been prescribed for epilepsy or weight reduction.
Case summary
A 24-year-old woman and a 25-year-old woman, both previously devoid of ocular problems, visited our hospital with blurry vision after taking topiramate for weight reduction. A thorough medical history review and ocular examinations, including a slit lamp examination, were performed.
Conclusions
Slit-lamp examinations revealed forward displacement of the lens-iris diaphragm, which resulted in myopia and anterior chamber shallowing. Discontinuation of topiramate and the administration of cycloplegic agents successfully resolved the symptoms.
关键词：Acute myopia; Cycloplegic agent; topiramate