To report three cases of Urrets ‐ Zavalia syndrome after deep lamellar keratoplasty.

A retrospective chart analysis of two men who underwent deep lamellar keraplasty after corneal chemical burns and one woman who was treated with deep lamellar keratoplasty due to lattice dystrophy was performed. To maintain the anterior chamber depth and prevent formation of a double anterior chamber after deep lamellar keratoplasty, air or gas (C₃F₈) was injected into the anterior chamber for all three cases. After injections of air or gas (C₃F₈) into the anterior chamber, pupillary blocks occurred and intraocular pressures increased. Afterwards, intraocular pressures were well ‐ controlled, but the pupil remained irreversibly fixed and dilated despite the use of miotics.

Urrets ‐ Zavalia syndrome, a postoperative complication, was first reported in a patient who underwent penetrating keratoplasty for keratoconus. This syndrome can also occur after deep lamellar keratoplasty on rare occasions.