文章基本信息
- 标题：Effect of Sodium Hyaluronate and Cyclosporine A on Tear Film in Dry Eye Syndrome
- 本地全文：下载
- 作者：Chang, In Boem ; Park, Jung Hyun ; Kim, Moo Sang 等
- 期刊名称：Journal of the Korean Ophthalmological Society
- 印刷版ISSN：0378-6471
- 出版年度：2013
- 卷号：54
- 期号：2
- 页码：231-236
- DOI：10.3341/jkos.2013.54.2.231
- 语种：Korean
- 出版社：The Korean Ophthalmological Society
- 摘要：Purpose
To evaluate the efficacy of topical 0.1% hyaluronate (HA) and 0.05% cyclosporine A on tear film parameters in dry eye syndrome patients.
MethodsPatients who were diagnosed with dry eye syndrome were treated with mbined with cyclosporine A (Group 2, 54 eyes). Ocular surface disease index (OSDI), tear film break-up time (BUT), Schirmer's test, and tear osmolarity were evaluated before treatment and at 1, 2, 3, and 6 months after treatment.
ResultsOSDI was significantly improved at 2 months after treatment and Schirmer's test results significantly improved at 1 month after treatment in both groups. The BUT was significantly improved 3 months after treatment in Group 1 and at 1 month after treatment in Group 2. Tear osmolarity significantly improved at 1 month after treatment in both groups, but continuously improved up to 6 months after treatment only in Group 2. The BUT and Schirmer's test showed greater improvements in Group 2 than in Group 1.
ConclusionsCombined treatment of topical 0.1% HA and 0.05% cyclosporine A may be more effective for improving dry eye syndrome.
- 关键词：Cyclosporine; Dry eye syndrome; Restasis; Tear osmolarity
