To investigate the influence of number and type of side effects as well as treatment period after the use of anti-glaucoma eye drops in patients with glaucoma.

A survey was conducted regarding the severity of ocular side effects after the use of anti-glaucoma eye drops in 528 patients with glaucoma. Side effects after using the eye drops included irritability, blurred vision, foreign body sensation, hyperemia, pinpricking sensation, itching, discomfort, pain, tearing, dry eye, and pigmentation. We analyzed the results to investigate the influence of number and type of side effects as well as treatment period.

The side effects after the use of anti-glaucoma eye drops were more severe and frequent in the patient groups using more than 1 eye drop ( p < 0.01) and in the patients with longer treatment period ( p < 0.01). Among patients using 1 eye drops, side effects developed frequently in patients using Ocucarpine®.

In patients with glaucoma, using more than 1 anti-glaucoma eye drop or having a longer treatment period resulted in more side effects. Similaryly, patients using only 1 eye drop of Ocu-carpine® induced more side effects.