To evaluate the change of visual quality after wearing orthokeratology lenses overnight.

This study included 13 patients (24 eyes) who wore orthokeratology lenses for the first time. Visual quality was assessed with the optical quality analysis system (OQAS) using the double-pass technique. The value of modulation transfer function (MTF) cutoff, Strehl ratio, and objective scatter index (OSI) were measured at baseline and 4 weeks after wearing the lenses.

The mean spherical equivalent decreased from -2.70 ± 1.03 diopters (D) to 0.03 ± 0.36 D after 4 weeks of wearing orthokeratology lenses and uncorrected visual acuity improved from log MAR 0.88 ± 0.17 to log MAR 0.03 ± 0.04. The MTF cutoff decreased from 38.20 ± 11.01 to 34.79 ± 10.30 and the Strehl ratio decreased from 0.24 ± 0.07 to 0.21 ± 0.07 but without statistical significance. The OSI significantly increased from 0.38 ± 0.19 to 0.72 ± 0.40 after wearing orthokeratology lenses.

Orthokeratology lenses were effective for correction of myopia and astigmatism. The OSI increased after wearing the lenses, but MFT cutoff and Strehl ratios were not affected.