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  • 标题:Clinical manifestations patterns of allergic disease in Korean children under the age of 6: multi-center study
  • 本地全文:下载
  • 作者:Kim, Dong Il ; Yang, Hyeon Jong ; Park, Young Mean
  • 期刊名称:Korean Journal of Pediatrics
  • 印刷版ISSN:1738-1061
  • 出版年度:2008
  • 卷号:51
  • 期号:6
  • 页码:640-645
  • DOI:10.3345/kjp.2008.51.6.640
  • 语种:Korean
  • 出版社:The Korean Pediatric Society
  • 摘要:Purpose

    It is widely known that allergic diseases progress through an allergic march. However, there have not been any recent reports in Korea on how the diseases progress.

    Methods

    Parents who visited one of the Pediatric Allergy Clinics of four university hospitals in Seoul with a child under the age of 6 years during the period from May 1-30, 2006 were asked to complete a questionnaire.

    Results

    A total of 229 parents answered the questionnaire about their children, of which 122 were male and 107 were female. The most common allergic disease before 2 years of age was atopic dermatitis (79%). Meanwhile, in 2- to 4-year age group, allergic rhinitis (38%) and asthma (37%) were predominant. The most common allergic disease in the 4- to 6-year age group was asthma (72%), followed by allergic rhinitis (64%). Seventy-three percent of the children had a family history of allergic disease, most often in the fathers (39%). Among patients with allergic rhinitis, 50% had experienced asthma in their earlier days and 30% had experienced atopic dermatitis. In addition, 57% of the children with asthma had suffered from atopic dermatitis. Parents believed that asthma was the most serious allergic disease.

    Conclusion

    In the present study, allergic disease showed a tendency to march from atopic dermatitis to asthma and then to allergic rhinitis. Early diagnosis and treatment of atopic dermatitis is, therefore, considered important for prevention of the allergic march.

  • 关键词:Allergic march; Questionnaire; Multicenter study
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