Colon barotrauma can be mostly caused by elevated intraluminal pressure. Air insufflation during colonoscopy procedure is the most common cause of iatrogenic colon barotrauma. Cat scratch colon can usually be seen in the mild type of colon barotrauma, and colon perforation can be seen in the severe type. We presently report a case of non-iatrogenic colon barotrauma caused by industrial compressed air. Multiple linear mucosal ulcers were noted in the recto-sigmoid colon, but the colon was not perforated. The patient was discharged without any further complications after conservative treatments.