首页    期刊浏览 2024年07月08日 星期一
登录注册

文章基本信息

  • 标题:In vitro biological evaluation of 100 selected methanol extracts from the traditional medicinal plants of Asia
  • 本地全文:下载
  • 作者:Li, Chunmei ; Wang, Myeong-Hyeon
  • 期刊名称:Nutrition Research and Practice
  • 印刷版ISSN:1976-1457
  • 出版年度:2014
  • 卷号:8
  • 期号:2
  • 页码:151-157
  • DOI:10.4162/nrp.2014.8.2.151
  • 语种:English
  • 出版社:KoreaMed Synapse
  • 摘要:BACKGROUND/OBJECTIVES

    In Asia, various medicinal plants have been used as the primary sources in the health care regimen for thousands of years. In recent decades, various studies have investigated the biological activity and potential medicinal value of the medicinal plants. In this study, 100 methanol extracts from 98 plant species were evaluated for their biological activities.

    MATERIALS/METHODS

    The research properties, including 1,1-diphenyl-2-pic-rylhydrazyl (DPPH) radical scavenging activity, α-glucosidase and α-tyrosinase inhibitory effects, anti-inflammatory activity, and anticancer activity were evaluated for the selected extracts.

    RESULTS

    Fifteen of the extracts scavenged more than 90% of the DPPH radical. Among the extracts, approximately 20 extracts showed a strong inhibitory effect on α-glucosidase, while most had no effect on α-tyrosinase. In addition, 52% of the extracts showed low toxicity to normal cells, and parts of the extracts exhibited high anti-inflammatory and anticancer activities on the murine macrophage cell (RAW 264.7) and human colon cancer cell (HT-29) lines, respectively.

    CONCLUSIONS

    Our findings may contribute to further nutrition and pharmacological studies. Detailed investigations of the outstanding samples are currently underway.

  • 关键词:Medicinal plants; antioxidant; anti-α-glucosidase; anti-inflammatory; anticancer
国家哲学社会科学文献中心版权所有