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  • 标题:A Giant Sebaceous Epithelioma on the Scalp: A Case Report
  • 本地全文:下载
  • 作者:Kim, Eun Yeon ; Kim, Sun Goo ; Kim, Yu Jin
  • 期刊名称:Archives of Craniofacial Surgery
  • 印刷版ISSN:2287-1152
  • 出版年度:2012
  • 卷号:13
  • 期号:1
  • 页码:76-79
  • DOI:10.7181/acfs.2012.13.1.76
  • 语种:Korean
  • 出版社:KoreaMed Synapse
  • 摘要:Purpose

    Sebaceous epithelioma (sebaceoma) is a benign tumor with sebaceous differentiation. It presents primarily as a yellowish papule or nodule on the face and scalp. It must be differentiated from basal cell carcinoma and other appendageal tumors. We report a giant sebaceous epithelioma on the scalp and describe the immunohistochemical character of the cells in sebaceous epithelioma to epithelial membrane antigen (EMA).

    Methods

    A 55-year-old-man who presented with 5-cm-diameter 2-cm-height, round shape exophytic ulcerated tumor on his head presented for treatment. The patient had noticed the lesion 40 years prior as a small yellowish plaque and 18 months ago, the plaque started to grow progressively larger. We excised the lesion with 1 cm resection margin, considering the possibility of malignancy because this lesion grossly resembled basal cell carcinoma (BCC). The defect was repaired with the use of a split-thickness skin graft.

    Results

    When we excised the lesion, the margin was clear. Histology showed nodules that consisted of an admixture of basaloid cells and mature adipocytes lacking an organized lobular architecture. Strong expression of EMA on mature adipose cells confirmed the differential diagnosis from BCC with sebaceous differentiation because of the absence of a nuclear palisade pattern and cleft-like spaces on the hematoxylin and eosin (H&E) section.

    Conclusion

    We treated the giant sebaceous epithelioma on the scalp with surgical excision and a split-thickness skin graft. It is important to know that the diagnosis of sebaceous epithelioma should be made based on the histologic pattern of the H&E section. Immunohistochemistry with EMA can help to confirm the differential diagnosis between sebaceous epithelioma and BCC.

  • 关键词:Sebaceous epithelioma; Basal cell carcinoma
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